Neutralization positive but apparent false-positive hepatitis B surface antigen in a blood donor following influenza vaccination.
Identifieur interne : 000260 ( Main/Exploration ); précédent : 000259; suivant : 000261Neutralization positive but apparent false-positive hepatitis B surface antigen in a blood donor following influenza vaccination.
Auteurs : Mark Bigham [Canada] ; Arjuna Ponnampalam [Canada]Source :
- Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis [ 1473-0502 ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
- effets indésirables : Vaccination, Vaccins antigrippaux.
- sang : Antigènes de surface du virus de l'hépatite B.
- Adulte, Canada, Donneurs de sang, Enquêtes et questionnaires, Faux positifs, Femelle, Grippe humaine, Humains, Tests de neutralisation.
- Wicri :
- geographic : Canada.
English descriptors
- KwdEn :
- MESH :
- chemical , adverse effects : Influenza Vaccines.
- chemical , blood : Hepatitis B Surface Antigens.
- geographic : Canada.
- adverse effects : Vaccination.
- prevention & control : Influenza, Human.
- Adult, Blood Donors, False Positive Reactions, Female, Humans, Neutralization Tests, Surveys and Questionnaires.
Abstract
We report a case of transient, confirmed positive hepatitis B surface antigen (HBsAg) in a 25 year old long term Canadian Blood Services (CBS) donor, who reported receiving 2011-2012 seasonal trivalent (A/H1N1, A/H3N2, Influenza B) inactivated influenza vaccine two days before donation. To our knowledge, this report is the first published case implicating influenza vaccine as a possible factor in false-positive HBsAg test results. Seasonal incidence of repeat-reactive HBsAg among CBS donors suggests a potential contributory role of influenza vaccine or community acquired infection. We speculate that influenza vaccine may rarely be associated with sporadic, transient, false-positive HBsAg results.
DOI: 10.1016/j.transci.2013.10.008
PubMed: 24268563
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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To our knowledge, this report is the first published case implicating influenza vaccine as a possible factor in false-positive HBsAg test results. Seasonal incidence of repeat-reactive HBsAg among CBS donors suggests a potential contributory role of influenza vaccine or community acquired infection. We speculate that influenza vaccine may rarely be associated with sporadic, transient, false-positive HBsAg results. </div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24268563</PMID><DateCompleted><Year>2015</Year><Month>04</Month><Day>13</Day></DateCompleted><DateRevised><Year>2015</Year><Month>11</Month><Day>19</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">1473-0502</ISSN><JournalIssue CitedMedium="Internet"><Volume>50</Volume><Issue>1</Issue><PubDate><Year>2014</Year><Month>Feb</Month></PubDate></JournalIssue><Title>Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis</Title><ISOAbbreviation>Transfus. Apher. Sci.</ISOAbbreviation></Journal><ArticleTitle>Neutralization positive but apparent false-positive hepatitis B surface antigen in a blood donor following influenza vaccination.</ArticleTitle><Pagination><MedlinePgn>92-4</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.transci.2013.10.008</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S1473-0502(13)00327-3</ELocationID><Abstract><AbstractText>We report a case of transient, confirmed positive hepatitis B surface antigen (HBsAg) in a 25 year old long term Canadian Blood Services (CBS) donor, who reported receiving 2011-2012 seasonal trivalent (A/H1N1, A/H3N2, Influenza B) inactivated influenza vaccine two days before donation. To our knowledge, this report is the first published case implicating influenza vaccine as a possible factor in false-positive HBsAg test results. Seasonal incidence of repeat-reactive HBsAg among CBS donors suggests a potential contributory role of influenza vaccine or community acquired infection. We speculate that influenza vaccine may rarely be associated with sporadic, transient, false-positive HBsAg results. </AbstractText><CopyrightInformation>Copyright © 2013 Elsevier Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bigham</LastName><ForeName>Mark</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Canadian Blood Services, BC & Yukon Centre, Vancouver, British Columbia, Canada. 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